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Lipid Raft-Dependent FcεRI Ubiquitination Regulates Receptor Endocytosis through the Action of Ubiquitin Binding Adaptors

The best characterized role for ubiquitination of membrane receptors is to negatively regulate signaling by targeting receptors for lysosomal degradation. The high affinity receptor for IgE (FcεRI) expressed on mast cells and basophils is rapidly ubiquitinated upon antigen stimulation. However, the...

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書誌詳細
主要な著者: Molfetta, Rosa, Gasparrini, Francesca, Peruzzi, Giovanna, Vian, Laura, Piccoli, Mario, Frati, Luigi, Santoni, Angela, Paolini, Rossella
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680016/
https://ncbi.nlm.nih.gov/pubmed/19440386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005604
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