Lipid Raft-Dependent FcεRI Ubiquitination Regulates Receptor Endocytosis through the Action of Ubiquitin Binding Adaptors

The best characterized role for ubiquitination of membrane receptors is to negatively regulate signaling by targeting receptors for lysosomal degradation. The high affinity receptor for IgE (FcεRI) expressed on mast cells and basophils is rapidly ubiquitinated upon antigen stimulation. However, the...

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Detaylı Bibliyografya
Asıl Yazarlar: Molfetta, Rosa, Gasparrini, Francesca, Peruzzi, Giovanna, Vian, Laura, Piccoli, Mario, Frati, Luigi, Santoni, Angela, Paolini, Rossella
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2009
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680016/
https://ncbi.nlm.nih.gov/pubmed/19440386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005604
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