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Sensing Caspase 3 Activity with Quantum Dot-Fluorescent Protein Assemblies

We demonstrate the use of a hybrid fluorescent protein semiconductor quantum dot (QD) sensor capable of specifically monitoring caspase 3 proteolytic activity. mCherry monomeric red fluorescent protein engineered to express an N-terminal caspase 3 cleavage site was ratiometrically self-assembled to...

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Détails bibliographiques
Auteurs principaux: Boeneman, Kelly, Mei, Bing C., Dennis, Allison M., Bao, Gang, Deschamps, Jeffrey R., Mattoussi, Hedi, Medintz, Igor L.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679970/
https://ncbi.nlm.nih.gov/pubmed/19243181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja809721j
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