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IL-15 independent maintenance of virus-specific CD8(+) T cells in the CNS during chronic infection
The role of IL-15 in T cell survival was examined during chronic CNS coronavirus infection. Similar numbers of virus-specific CD8(+) T cells were retained in the CNS of IL-15(−/−) and wt mice, consistent with loss of IL-2/15 receptor (CD122) expression. IL-15 deficiency also had no affect on IL-7 re...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier B.V.
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2679951/ https://ncbi.nlm.nih.gov/pubmed/19106006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2008.11.005 |
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