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Formation of molecular species of mitochondrial cardiolipin. 1. A novel transacylation mechanism to shuttle fatty acids between sn-1 and sn-2 positions of multiple phospholipid species

Mitochondrial cardiolipin undergoes extensive remodeling of its acyl groups to generate uniformly substituted species, such as tetralinoleoyl-cardiolipin, but the mechanism of this remodeling has not been elucidated, except for the fact that it requires tafazzin. Here we show that purified recombina...

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Detalhes bibliográficos
Main Authors: Malhotra, Ashim, Xu, Yang, Ren, Mindong, Schlame, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679859/
https://ncbi.nlm.nih.gov/pubmed/19416660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2009.01.004
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