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NR2B receptor blockade inhibits pain-related sensitization of amygdala neurons

Pain-related sensitization and synaptic plasticity in the central nucleus of the amygdala (CeA) depend on the endogenous activation of NMDA receptors and phosphorylation of the NR1 subunit through a PKA-dependent mechanism. Functional NMDA receptors are heteromeric assemblies of NR1 with NR2A-D or N...

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Bibliografiske detaljer
Main Authors: Ji, Guangchen, Horváth, Csilla, Neugebauer, Volker
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679723/
https://ncbi.nlm.nih.gov/pubmed/19400952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-5-21
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