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Drosophila Lethal Giant Larvae Neoplastic Mutant as a Genetic Tool for Cancer Modeling
Drosophila lethal giant larvae (lgl) is a tumour suppressor gene whose function in establishing apical-basal cell polarity as well as in exerting proliferation control in epithelial tissues is conserved between flies and mammals. Individuals bearing lgl null mutations show a gradual loss of tissue a...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Bentham Science Publishers Ltd.
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2679652/ https://ncbi.nlm.nih.gov/pubmed/19440511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/138920208784340786 |
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