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Integrating genetic and gene expression data: application to cardiovascular and metabolic traits in mice

The millions of common DNA variations that occur in the human population, or among inbred strains of mice and rats, perturb the expression (transcript levels) of a large fraction of the genes expressed in a particular tissue. The hundreds or thousands of common cis-acting variations that occur in th...

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Detalhes bibliográficos
Main Authors: Drake, Thomas A., Schadt, Eric E., Lusis, Aldons J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer New York 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679634/
https://ncbi.nlm.nih.gov/pubmed/16783628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-005-0175-z
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