Congenital Hypomyelinating Neuropathy with Lethal Conduction Failure in Mice Carrying the Egr2 I268N Mutation

Mouse models of human disease are helpful for understanding the pathogenesis of the disorder and ultimately for testing potential therapeutic agents. Here, we describe the engineering and characterization of a mouse carrying the I268N mutation in Egr2, observed in patients with recessively inherited...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Baloh, Robert H., Strickland, Amy, Ryu, Elizabeth, Le, Nam, Fahrner, Timothy, Yang, Mao, Nagarajan, Rakesh, Milbrandt, Jeffrey
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2009
Teme:
Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679588/
https://ncbi.nlm.nih.gov/pubmed/19244508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2168-08.2009
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki