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Effects of baclofen on conditioned rewarding and discriminative stimulus effects of nicotine in rats

Neurochemical studies suggest that baclofen, an agonist at GABA(B) receptors, may be useful for treatment of nicotine dependence. However, its ability to selectively reduce nicotine’s abuse-related behavioral effects remains in question. We assessed effects of baclofen doses ranging from 0.1 to 3 mg...

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Detalhes bibliográficos
Main Authors: Le Foll, Bernard, Wertheim, Carrie E., Goldberg, Steven R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679513/
https://ncbi.nlm.nih.gov/pubmed/18682277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2008.07.074
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