Novel Protective Mechanism against Irreversible Hyperoxidation of Peroxiredoxin: N(α)-TERMINAL ACETYLATION OF HUMAN PEROXIREDOXIN II

Peroxiredoxins (Prxs) are a group of peroxidases containing a cysteine thiol at their catalytic site. During peroxidase catalysis, the catalytic cysteine, referred to as the peroxidatic cysteine (C(P)), cycles between thiol (C(P)-SH) and disulfide (–S–S–) states via a sulfenic (C(P)-SOH) intermediat...

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Hlavní autoři: Seo, Jae Ho, Lim, Jung Chae, Lee, Duck-Yeon, Kim, Kyung Seok, Piszczek, Grzegorz, Nam, Hyung Wook, Kim, Yu Sam, Ahn, Taeho, Yun, Chul-Ho, Kim, Kanghwa, Chock, P. Boon, Chae, Ho Zoon
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2009
Témata:
Enzyme Catalysis and Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679445/
https://ncbi.nlm.nih.gov/pubmed/19286652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M900641200
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