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Functional characterization of human oncoprotein gankyrin in Zebrafish
Gankyrin is an oncoprotein containing seven ankyrin repeats that is overexpressed in hepatocellular carcinoma (HCC). Gankyrin binds to Mdm2, which results in accelerated ubiquitylation via degradation of p53, and it also plays an important role in cell proliferation. However, little is known about t...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Korean Society of Medical Biochemistry and Molecular Biology
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2679278/ https://ncbi.nlm.nih.gov/pubmed/19287195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2009.41.1.002 |
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