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Functional characterization of human oncoprotein gankyrin in Zebrafish

Gankyrin is an oncoprotein containing seven ankyrin repeats that is overexpressed in hepatocellular carcinoma (HCC). Gankyrin binds to Mdm2, which results in accelerated ubiquitylation via degradation of p53, and it also plays an important role in cell proliferation. However, little is known about t...

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Detalhes bibliográficos
Main Authors: Kim, So Yeon, Hur, Wonhee, Choi, Jung-Eun, Kim, Daniel, Wang, Jin Sang, Yoon, Hye-Yeon, Piao, Lian-Shu, Yoon, Seung Kew
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society of Medical Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679278/
https://ncbi.nlm.nih.gov/pubmed/19287195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2009.41.1.002
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