Simvastatin inhibits induction of matrix metalloproteinase-9 in rat alveolar macrophages exposed to cigarette smoke extract

Matrix metalloproteinase-9 (MMP-9) may play an important role in emphysematous change in chronic obstructive pulmonary disease (COPD), one of the leading causes of mortality and morbidity worldwide. We previously reported that simvastatin, an inhibitor of HMG-CoA reductase, attenuates emphysematous...

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Detalhes bibliográficos
Main Authors: Kim, Sang-Eun, Thuy, Tran Thi Thanh, Lee, Ji-Hyun, Ro, Jai Youl, Bae, Young-An, Kong, Yoon, Ahn, Jee-Yin, Lee, Dong-Soon, Oh, Yeon-Mock, Lee, Sang-Do, Lee, Yun-Song
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society of Medical Biochemistry and Molecular Biology 2009
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679231/
https://ncbi.nlm.nih.gov/pubmed/19299917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2009.41.4.031
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