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Lack of age and gender effects on single-dose pharmacokinetics of tomopenem (RO4908463/CS-023), a novel carbapenem

AIMS: To investigate the effect of age and gender on the tolerability, safety and pharmacokinetics (PK) of tomopenem (RO4908463/CS-023), a novel carbapenem antibiotic, and its major metabolite. METHODS: Forty-two subjects were assigned to one of the following three groups: young men, elderly men and...

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Detalhes bibliográficos
Main Authors: Mallalieu, Navita L, Lennon, Siân, Guy, Thorold, Liu, Mei, Luedin, Eric, Davies, Brian E
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679112/
https://ncbi.nlm.nih.gov/pubmed/19371322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2009.03367.x
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