CXCL12 Increases Human Neural Progenitor Cell Proliferation Through Akt-1/FOXO3a Signaling Pathway

CXCL12, a ligand for the chemokine receptor CXCR4, is well known in mediating neural progenitor cell (NPC) migration during neural development. However, the effects of CXCL12 on human NPC proliferation and its associated signaling pathways remain unclear. The transcription factor FOXO3a, a downstrea...

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Autori principali: Wu, Yumei, Peng, Hui, Cui, Min, Whitney, Nicholas P., Huang, Yunlong, Zheng, Jialin C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679099/
https://ncbi.nlm.nih.gov/pubmed/19302476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2009.06043.x
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