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Complexity in the genetic architecture of leukoaraiosis in hypertensive sibships from the GENOA Study

BACKGROUND: Subcortical white matter hyperintensity on magnetic resonance imaging (MRI) of the brain, referred to as leukoaraiosis, is associated with increased risk of stroke and dementia. Hypertension may contribute to leukoaraiosis by accelerating the process of arteriosclerosis involving penetra...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Smith, Jennifer A, Turner, Stephen T, Sun, Yan V, Fornage, Myriam, Kelly, Reagan J, Mosley, Thomas H, Jack, Clifford R, Kullo, Iftikhar J, Kardia, Sharon LR
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679055/
https://ncbi.nlm.nih.gov/pubmed/19351393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-2-16
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