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Bone sialoprotein does not interact with pro-gelatinase A (MMP-2) or mediate MMP-2 activation

BACKGROUND: A recent model for activation of the zymogen form of matrix metalloproteinase 2 (MMP-2, also known as gelatinase A) has suggested that interactions between the SIBLING protein bone sialoprotein (BSP) and MMP-2 leads to conformational change in MMP-2 that initiates the conversion of the p...

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Detalhes bibliográficos
Main Authors: Hwang, Queena, Cheifetz, Sela, Overall, Christopher M, McCulloch, Christopher A, Sodek, Jaro
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679042/
https://ncbi.nlm.nih.gov/pubmed/19386107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-121
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