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Small molecule inhibitors of the Yersinia type III secretion system impair the development of Chlamydia after entry into host cells

BACKGROUND: Chlamydiae are obligate intracellular pathogens that possess a type III secretion system to deliver proteins into the host cell during infection. Small molecule inhibitors of type III secretion in Yersinia, termed INPs (Innate Pharmaceuticals AB) were reported to strongly inhibit Chlamyd...

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Detalhes bibliográficos
Main Authors: Muschiol, Sandra, Normark, Staffan, Henriques-Normark, Birgitta, Subtil, Agathe
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679026/
https://ncbi.nlm.nih.gov/pubmed/19383140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-9-75
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