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Broad mesodermal and endodermal deletion of Nodal at post-gastrulation stages results solely in left right axial defects
Nodal signaling is a critical regulator of multiple aspects of early vertebrate development including asymmetry along the left/right (LR) axis. To study Nodal function occurring specifically in the post-gastrulation embryo, we have used Cre/loxP based conditional mutagenesis. A floxed allele of Noda...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2678897/ https://ncbi.nlm.nih.gov/pubmed/18773491 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.21665 |
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