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Synthesis and characterization of a redox- and light-sensitive MRI contrast agent

A redox- and light-sensitive, T(1)-weighted magnetic resonance imaging (MRI) contrast agent which tethers a spiropyran(SP)/merocyanine(MC) motif to a Gd-DO3A moiety was synthesized and characterized. When in the dark, the probe is in its MC form which has an r(1) relaxivity of 2.51 mM(−1)s(−1) (60MH...

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Main Authors: Tu, Chuqiao, Osborne, Elizabeth A., Louie, Angelique Y.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678739/
https://ncbi.nlm.nih.gov/pubmed/20126289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2008.12.020
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