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Simulating the electrostatic guidance of the vectorial translocations in hexameric helicases and translocases

The molecular origin of the action of helicases is explored, starting with a model built based on the different X-ray structures of the large tumor antigen (LTag) hexameric helicase and a simplified model containing the ionized phosphate backbones of a single-strand DNA. The coupling between the pro...

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Autori principali: Liu, Hanbin, Shi, Yemin, Chen, Xiaojiang S., Warshel, Arieh
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678657/
https://ncbi.nlm.nih.gov/pubmed/19383795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900532106
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