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A gain in GABA(A) receptor synaptic strength in thalamus reduces oscillatory activity and absence seizures

Neural inhibition within the thalamus is integral in shaping thalamocortical oscillatory activity. Fast, synaptic inhibition is primarily mediated by activation of heteropentameric GABA(A) receptor complexes. Here, we examined the synaptic physiology and network properties of mice lacking GABA(A) re...

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Bibliographic Details
Main Authors: Schofield, Claude M., Kleiman-Weiner, Max, Rudolph, Uwe, Huguenard, John R.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678654/
https://ncbi.nlm.nih.gov/pubmed/19380748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811326106
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