Disruption of NMDAR-dependent burst firing by dopamine neurons provides selective assessment of phasic dopamine-dependent behavior

Midbrain dopamine (DA) neurons fire in 2 characteristic modes, tonic and phasic, which are thought to modulate distinct aspects of behavior. However, the inability to selectively disrupt these patterns of activity has hampered the precise definition of the function of these modes of signaling. Here,...

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Autori principali: Zweifel, Larry S., Parker, Jones G., Lobb, Collin J., Rainwater, Aundrea, Wall, Valerie Z., Fadok, Jonathan P., Darvas, Martin, Kim, Min J., Mizumori, Sheri J. Y., Paladini, Carlos A., Phillips, Paul E. M., Palmiter, Richard D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2009
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678650/
https://ncbi.nlm.nih.gov/pubmed/19342487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0813415106
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