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Regulated expression of the Leishmania major surface virulence factor lipophosphoglycan using conditionally destabilized fusion proteins

Surface glycoconjugates play important roles in the infectious cycle of Leishmania major, including the abundant lipophosphoglycan (LPG) implicated in parasite survival in the sand fly vector and the initial stages of establishment in the mammalian host macrophage. We describe a system for inducible...

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Detalhes bibliográficos
Main Authors: Madeira da Silva, Luciana, Owens, Katherine L., Murta, Silvane M. F., Beverley, Stephen M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678649/
https://ncbi.nlm.nih.gov/pubmed/19383793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901698106
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