Sequencing of TGF-β pathway genes in familial cases of intracranial aneurysm

BACKGROUND AND PURPOSE: Familial aggregation of intracranial aneurysms (IA) strongly suggests a genetic contribution to pathogenesis. However, genetic risk factors have yet to be defined. For families affected by aortic aneurysms, specific gene variants have been identified, many affecting the recep...

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Bibliographic Details
Main Authors: Santiago-Sim, Teresa, Mathew-Joseph, Sumy, Pannu, Hariyadarshi, Milewicz, Dianna M., Seidman, Christine E., Seidman, J.G., Kim, Dong H.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678560/
https://ncbi.nlm.nih.gov/pubmed/19299629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.108.540245
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