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Non-competitive androgen receptor inhibition in vitro and in vivo

Androgen receptor (AR) inhibitors are used to treat multiple human diseases, including hirsutism, benign prostatic hypertrophy, and prostate cancer, but all available anti-androgens target only ligand binding, either by reduction of available hormone or by competitive antagonism. New strategies are...

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Detalhes bibliográficos
Main Authors: Jones, Jeremy O., Bolton, Eric C., Huang, Yong, Feau, Clementine, Guy, R. Kiplin, Yamamoto, Keith R., Hann, Byron, Diamond, Marc I.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678452/
https://ncbi.nlm.nih.gov/pubmed/19363158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807282106
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