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Signatures of natural selection are not uniform across genes of innate immune system, but purifying selection is the dominant signature

We tested the opposing views concerning evolution of genes of the innate immune system that (i) being evolutionary ancient, the system may have been highly optimized by natural selection and therefore should be under purifying selection, and (ii) the system may be plastic and continuing to evolve un...

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Bibliographic Details
Main Authors: Mukherjee, Souvik, Sarkar-Roy, Neeta, Wagener, Diane K., Majumder, Partha P.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678448/
https://ncbi.nlm.nih.gov/pubmed/19359493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811357106
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