Single amino acid substitution in Plasmodium yoelii erythrocyte ligand determines its localization and controls parasite virulence

The major virulence determinant of the rodent malaria parasite, Plasmodium yoelii, has remained unresolved since the discovery of the lethal line in the 1970s. Because virulence in this parasite correlates with the ability to invade different types of erythrocytes, we evaluated the potential role of...

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Bibliographic Details
Main Authors: Otsuki, Hitoshi, Kaneko, Osamu, Thongkukiatkul, Amporn, Tachibana, Mayumi, Iriko, Hideyuki, Takeo, Satoru, Tsuboi, Takafumi, Torii, Motomi
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2009
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678433/
https://ncbi.nlm.nih.gov/pubmed/19346470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811313106
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