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Imaging adenoviral-directed reporter gene expression in living animals with positron emission tomography

We are developing quantitative assays to repeatedly and noninvasively image expression of reporter genes in living animals, using positron emission tomography (PET). We synthesized positron-emitting 8-[18F]fluoroganciclovir (FGCV) and demonstrated that this compound is a substrate for the herpes sim...

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Detalhes bibliográficos
Main Authors: Gambhir, Sanjiv S., Barrio, Jorge R., Phelps, Michael E., Iyer, Meera, Namavari, Mohammad, Satyamurthy, Nagichettiar, Wu, Lily, Green, Leeta A., Bauer, Eileen, MacLaren, Duncan C., Nguyen, Khoi, Berk, Arnold J., Cherry, Simon R., Herschman, Harvey R.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC26784/
https://ncbi.nlm.nih.gov/pubmed/10051642
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