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Hydrogen peroxide mediates the radiation-induced mutator phenotype in mammalian cells

Chronic oxidative stress has been associated with genomic instability following exposure to ionizing radiation (IR). However, data showing direct causal linkages between specific reactive oxygen species and the IR-induced mutator phenotype are lacking. The current study demonstrates that IR-induced...

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Autors principals: Dayal, Disha, Martin, Sean M., Limoli, Charles L., Spitz, Douglas R.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677991/
https://ncbi.nlm.nih.gov/pubmed/18352860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20071643
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