Erythrocyte Binding Protein PfRH5 Polymorphisms Determine Species-Specific Pathways of Plasmodium falciparum Invasion

Some human Plasmodium falciparum parasites, but not others, cause malaria in Aotus monkeys. To identify the basis for this variation, we crossed two clones that differ in A. nancymaae virulence and mapped inherited traits of infectivity to erythrocyte invasion by linkage analysis. A major pathway of...

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Hlavní autoři: Hayton, Karen, Gaur, Deepak, Liu, Anna, Takahashi, Jonathan, Henschen, Bruce, Singh, Subhash, Lambert, Lynn, Furuya, Tetsuya, Bouttenot, Rachel, Doll, Michelle, Nawaz, Fatima, Mu, Jianbing, Jiang, Lubin, Miller, Louis H., Wellems, Thomas E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677973/
https://ncbi.nlm.nih.gov/pubmed/18621009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2008.06.001
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