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Extracellular signal-regulated kinase (ERK) and protein kinase B (AKT) pathways involved in spinal cord stimulation (SCS)-induced vasodilation

BACKGROUND AND AIMS: SCS is used to improve peripheral circulation in selected patients with ischemia of the extremities. However the mechanisms are not fully understood. The present study investigated whether blockade of ERK and AKT activation modulated SCS-induced vasodilation. METHODS: A unipolar...

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Autori principali: Wu, Mingyuan, Komori, Naoka, Qin, Chao, Farber, Jay P., Linderoth, Bengt, Foreman, Robert D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677917/
https://ncbi.nlm.nih.gov/pubmed/18374907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2007.12.072
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