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Oxidative stress induces degradation of mitochondrial DNA
Mitochondrial DNA (mtDNA) is located in close proximity of the respiratory chains, which are the main cellular source of reactive oxygen species (ROS). ROS can induce oxidative base lesions in mtDNA and are believed to be an important cause of the mtDNA mutations, which accumulate with aging and in...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2677867/ https://ncbi.nlm.nih.gov/pubmed/19264794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp100 |
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