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Engineering transcription factors with novel DNA-binding specificity using comparative genomics

The transcriptional program for a gene consists of the promoter necessary for recruiting RNA polymerase along with neighboring operator sites that bind different activators and repressors. From a synthetic biology perspective, if the DNA-binding specificity of these proteins can be changed, then the...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Desai, Tasha A., Rodionov, Dmitry A., Gelfand, Mikhail S., Alm, Eric J., Rao, Christopher V.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677863/
https://ncbi.nlm.nih.gov/pubmed/19264798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp079
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