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Brain arteriovenous malformation biology relevant to hemorrhage and implication for therapeutic development

Brain arteriovenous malformations (AVM) cause intracranial hemorrhage (ICH). Molecular characterization of lesional tissue implicates angiogenic (VEGF, ANG-2, MMP-9) and inflammatory (cytokines and chemokines) pathways, but the pathogenesis remain obscure and medical therapy is lacking. Macrophage a...

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Bibliografiske detaljer
Main Authors: Kim, Helen, Pawlikowska, Ludmila, Chen, Yongmei, Su, Hua, Yang, Guo-Yuan, Young, William L.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677752/
https://ncbi.nlm.nih.gov/pubmed/19064791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.108.533216
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