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Clinical Efficacy and Toxicity of Anti-EGFR Therapy in Common Cancers

Epidermal growth factor receptor (EGFR) is a cell surface molecule and member of the ErbB family of receptor tyrosine kinases. Its activation leads to proliferation, antiapoptosis, and metastatic spread, making inhibition of this pathway a compelling target. In recent years, an increasing number of...

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Détails bibliographiques
Auteurs principaux: Harandi, Amir, Zaidi, Aisha S., Stocker, Abigail M., Laber, Damian A.
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677718/
https://ncbi.nlm.nih.gov/pubmed/19424511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2009/567486
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