Pivotal Role of the α(2A)-Adrenoceptor in Producing Inflammation and Organ Injury in a Rat Model of Sepsis

BACKGROUND: Norepinephrine (NE) modulates the responsiveness of macrophages to proinflammatory stimuli through the activation of adrenergic receptors (ARs). Being part of the stress response, early increases of NE in sepsis sustain adverse systemic inflammatory responses. The intestine is an importa...

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Detaylı Bibliyografya
Asıl Yazarlar: Miksa, Michael, Das, Padmalaya, Zhou, Mian, Wu, Rongqian, Dong, Weifeng, Ji, Youxin, Goyert, Sanna M., Ravikumar, Thanjavur S., Wang, Ping
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2009
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677660/
https://ncbi.nlm.nih.gov/pubmed/19430535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005504
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