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A two-step binding model proposed for the electrostatic interactions of ricin A chain with ribosomes
Ricin is a ribosome inactivating protein that catalytically removes a universally conserved adenine from the α-sarcin/ricin loop (SRL) of the 28S rRNA. We recently showed that ricin A chain (RTA) interacts with the P1 and P2 proteins of the ribosomal stalk to depurinate the SRL in yeast. Here we exa...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2677637/ https://ncbi.nlm.nih.gov/pubmed/19292477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi802371h |
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