Učitavanje...
N-APP binds DR6 to cause axon pruning and neuron death via distinct caspases
Naturally-occurring axonal pruning and neuronal cell death help sculpt neuronal connections during development, but their mechanistic basis remains poorly understood. We report that Amyloid Precursor Protein (APP) and Death Receptor 6 (DR6) activate a widespread caspase-dependent self-destruction pr...
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| Glavni autori: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2009
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2677572/ https://ncbi.nlm.nih.gov/pubmed/19225519 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07767 |
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