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Age-associated leukoaraiosis and cortical cholinergic deafferentation

OBJECTIVE: To investigate the relationship between age-associated MRI leukoaraiosis or white matter hyperintensities (WMH) and cortical acetylcholinesterase (AChE) activity. BACKGROUND: One possible mechanism of cognitive decline in elderly individuals with leukoaraiosis is disruption of cholinergic...

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Detalhes bibliográficos
Main Authors: Bohnen, N I., Müller, M L.T.M., Kuwabara, H, Constantine, G M., Studenski, S A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Academy of Neurology 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677506/
https://ncbi.nlm.nih.gov/pubmed/19380700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e3181a187c6
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