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Mutations in GBA are associated with familial Parkinson disease susceptibility and age at onset

OBJECTIVE: To characterize sequence variation within the glucocerebrosidase (GBA) gene in a select subset of our sample of patients with familial Parkinson disease (PD) and then to test in our full sample whether these sequence variants increased the risk for PD and were associated with an earlier o...

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Detalhes bibliográficos
Main Authors: Nichols, W C., Pankratz, N, Marek, D K., Pauciulo, M W., Elsaesser, V E., Halter, C A., Rudolph, A, Wojcieszek, J, Pfeiffer, R F., Foroud, T
Formato: Artigo
Idioma:Inglês
Publicado em: American Academy of Neurology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677501/
https://ncbi.nlm.nih.gov/pubmed/18987351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/01.wnl.0000327823.81237.d1
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