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The common BDNF polymorphism may be a modifier of disease severity in Rett syndrome
BACKGROUND: Rett syndrome (RTT) is caused by mutations in the transcriptional repressor methyl CpG-binding protein 2 (MECP2). Brain-derived neurotrophic factor (BDNF) is a neurotrophic factor playing a major role in neuronal survival, neurogenesis, and plasticity, and it has been shown that BDNF exp...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Academy of Neurology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2677489/ https://ncbi.nlm.nih.gov/pubmed/19349604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/01.wnl.0000345664.72220.6a |
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