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Neuropathologic intermediate phenotypes enhance association to Alzheimer susceptibility alleles

OBJECTIVE: The identification of susceptibility alleles to risk of Alzheimer disease (AD) is a major public health priority. Using apolipoprotein E genotype (APOE), we examined whether neuropathologic intermediate phenotypes, the pathology underlying clinical AD that presumably lies intermediate in...

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Autori principali: Bennett, David A., De Jager, Philip L., Leurgans, Sue E., Schneider, Julie A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Academy of Neurology 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677477/
https://ncbi.nlm.nih.gov/pubmed/19398704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e3181a2e87d
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