Attaching and Effacing Escherichia coli Downregulate DNA Mismatch Repair Protein In Vitro and Are Associated with Colorectal Adenocarcinomas in Humans

BACKGROUND: Mucosa-associated Escherichia coli are frequently found in the colonic mucosa of patients with colorectal adenocarcinoma, but rarely in healthy controls. Chronic mucosal E. coli infection has therefore been linked to colonic tumourigenesis. E. coli strains carrying eae (encoding the bact...

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Main Authors: Maddocks, Oliver D. K., Short, Abigail J., Donnenberg, Michael S., Bader, Scott, Harrison, David J.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2009
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677459/
https://ncbi.nlm.nih.gov/pubmed/19436735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005517
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