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Crossreactive recognition of viral, self, and bacterial peptide ligands by human class I-restricted cytotoxic T lymphocyte clonotypes: Implications for molecular mimicry in autoimmune disease

The immunodominant, CD8(+) cytotoxic T lymphocyte (CTL) response to the HLA-B8-restricted peptide, RAKFKQLL, located in the Epstein–Barr virus immediate-early antigen, BZLF1, is characterized by a diverse T cell receptor (TCR) repertoire. Here, we show that this diversity can be partitioned on the b...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Misko, Ihor S., Cross, Simone M., Khanna, Rajiv, Elliott, Suzanne L., Schmidt, Christopher, Pye, Stephanie J., Silins, Sharon L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26774/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10051632/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.5.2279
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