p75(NTR) mediates ephrin-A reverse signaling required for axon repulsion and mapping

Reverse signaling by ephrin-As upon binding EphAs controls axon guidance and mapping. Ephrin-As are GPI-anchored to the membrane, requiring that they complex with transmembrane proteins that transduce their signals. We show that the p75 neurotrophin receptor (NTR) serves this role in retinal axons....

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Bibliographic Details
Main Authors: Lim, Yoo-Shick, McLaughlin, Todd, Sung, Tsung-Chang, Santiago, Alicia, Lee, Kuo-Fen, O’Leary, Dennis D.M.
Format: Artigo
Language:Inglês
Published: 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677386/
https://ncbi.nlm.nih.gov/pubmed/18786358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2008.07.032
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