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p75(NTR) mediates ephrin-A reverse signaling required for axon repulsion and mapping
Reverse signaling by ephrin-As upon binding EphAs controls axon guidance and mapping. Ephrin-As are GPI-anchored to the membrane, requiring that they complex with transmembrane proteins that transduce their signals. We show that the p75 neurotrophin receptor (NTR) serves this role in retinal axons....
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2677386/ https://ncbi.nlm.nih.gov/pubmed/18786358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2008.07.032 |
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