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Synthesis of Enantiomerically Pure (S)-Methanocarbaribo Uracil Nucleoside Derivatives for Use as Antiviral Agents and P2Y Receptor Ligands

[Image: see text] We have developed an approach toward enantiomerically pure (S)-methanocarba ribonucleosides based on several functional group transformations on a sensitive bicyclo[3.1.0]hexane system. D-Ribose was transformed into methanocarba alcohol 3 followed by conversion of the OH group to a...

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Detalhes bibliográficos
Main Authors: Melman, Artem, Zhong, Minghong, Marquez, Victor E., Jacobson, Kenneth A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677375/
https://ncbi.nlm.nih.gov/pubmed/18811198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo801224j
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