Growth of cancer cell lines under stem cell-like conditions has the potential to unveil therapeutic targets

Malignant tumors comprise a small proportion of cancer-initiating cells (CIC), capable of sustaining tumor formation and growth. CIC are the main potential target for anticancer therapy. However, the identification of molecular therapeutic targets in CIC isolated from primary tumors is an extremely...

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Main Authors: Rappa, Germana, Mercapide, Javier, Anzanello, Fabio, Prasmickaite, Lina, Xi, Yaguang, Ju, Jingfang, Fodstad, Oystein, Lorico, Aurelio
Format: Artigo
Jezik:Inglês
Izdano: 2008
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677207/
https://ncbi.nlm.nih.gov/pubmed/18423605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2008.03.008
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