Bioavailability of Orally Administered rhGM-CSF: A Single-Dose, Randomized, Open-Label, Two-Period Crossover Trial

BACKGROUND: Recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) is usually administered by injection, and its oral administration in a clinical setting has been not yet reported. Here we demonstrate the bioavailability of orally administered rhGM-CSF in healthy volunteers....

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Zhang, Wenping, Lv, Zhengbing, Nie, Zuoming, Chen, Guogang, Chen, Jian, Sheng, Qing, Yu, Wei, Jin, Yongfeng, Wu, Xiangfu, Zhang, Yaozhou
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2009
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677157/
https://ncbi.nlm.nih.gov/pubmed/19434235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005353
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