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BILE SALT-INDUCED PRO-OXIDANT LIVER DAMAGE PROMOTES TRANSPLANTED CELL PROLIFERATION FOR CORRECTING WILSON DISEASE IN THE LEC RAT MODEL

Insights into disease-specific mechanisms for liver repopulation are needed for cell therapy. To understand the efficacy of pro-oxidant hepatic perturbations in Wilson disease, we studied Long-Evans Cinnamon rats with copper toxicosis under several conditions. Hepatocytes from healthy Long-Evans Ago...

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Detalhes bibliográficos
Main Authors: Joseph, Brigid, Kapoor, Sorabh, Schilsky, Michael L., Gupta, Sanjeev
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677114/
https://ncbi.nlm.nih.gov/pubmed/19185006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.22792
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