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Ovarian neoplasm development by 7,12-dimethylbenz[a]anthracene (DMBA) in a chemically-induced rat model of ovarian failure

OBJECTIVES: The objectives were to determine the time course for ovarian failure in rats caused by 4-vinylcyclohexene diepoxide (VCD) and develop a model for ovarian cancer in which ovarian neoplasms were chemically induced in an animal that was follicle depleted, but retained residual ovarian tissu...

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Autors principals: Hoyer, PB, Davis, JR, Bedrnicek, JB, Marion, SL, Christian, PJ, Barton, JK, Brewer, MA
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677070/
https://ncbi.nlm.nih.gov/pubmed/19150572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2008.12.013
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